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Proceedings Paper

Electrophysiological Correlates Of Argon Laser Ablation Of Myocardium
Author(s): J. C. Merillat; M. D. Stern; J. H. Levine; H. F. Weisman; J. F. Spear; E. N. Moore; A. A. Kadish; J. Fonger; R. Guzman; T. Guarnieri
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Paper Abstract

Myocardial ablation is a newly developing technique in the treatment of cardiac arrhythmias. Laser ablation in animal models has been associated with fewer procedural arrhythmias and more focal areas of myocardial injury. The effect of Argon laser ablation on canine epicardial preparations was studied. Single cell, microelectrode techniques were used to record action potential characteristics before and after argon laser ablation. Additionally, infrared micro-thermography was recorded during ablation to establish the superficial thermal characteristics of Argon laser ablation. Focal areas of action potential abnormality were found only at a distance of less than 5 mm from the laser crater edge. Action potential abnormalities occured only in areas where the superficial temperatures exceeded 60 degrees C. The focal nature of the injury as shown by action potential recordings may explain the less frequent association with arrhythmias and myocardial dysfunction.

Paper Details

Date Published: 1 April 1987
PDF: 2 pages
Proc. SPIE 0713, Optical Fibers in Medicine II, (1 April 1987); doi: 10.1117/12.937373
Show Author Affiliations
J. C. Merillat, Johns Hopkins Hospital (United States)
M. D. Stern, JOhns Hopkins Hospital (United States)
J. H. Levine, Johns Hopkins Hospital (United States)
H. F. Weisman, Johns Hopkins Hospital (United States)
J. F. Spear, Johns Hopkins Hospital (United States)
E. N. Moore, Johns Hopkins Hospital (United States)
A. A. Kadish, Johns Hopkins Hospital (United States)
J. Fonger, Johns Hopkins Hospital (United States)
R. Guzman, Johns Hopkins Hospital (United States)
T. Guarnieri, Johns Hopkins Hospital (United States)

Published in SPIE Proceedings Vol. 0713:
Optical Fibers in Medicine II
Abraham Katzir, Editor(s)

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