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Proceedings Paper

In Vivo Measurements On Human Lens Using Quasielastic Light Scattering
Author(s): Peter C. Magnante; Leo T. Chylack; George B. Benedek; Teodosio Libondi
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Paper Abstract

Quasi-elastic light scattering is a useful method to determine the size distribution of sub-micron particles in fluids. We have applied this technique to measure in vivo changes in the association of human lens protein constituents that occur with aging and cataractogenesis. The autocorrelation function of the scattered light has been analyzed by a two component exponential where each component is characterized by an intensity and decay rate. Each pair of parameters is associated with one of two major protein compo-nents in the lens. Our results seem to be consistent with the model of progressive aggregation of the lens proteins as detected in vitro by other biochemical methods.

Paper Details

Date Published: 10 March 1987
PDF: 3 pages
Proc. SPIE 0712, Lasers in Medicine, (10 March 1987); doi: 10.1117/12.937336
Show Author Affiliations
Peter C. Magnante, Precision Optics Corporation (United States)
Leo T. Chylack, Massachusetts Eye & Ear Infirmary (United States)
George B. Benedek, Massachusetts Institute of Technology (United States)
Teodosio Libondi, First Medical School (Italy)

Published in SPIE Proceedings Vol. 0712:
Lasers in Medicine
Stephen N. Joffe; John A. Parrish, Editor(s)

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