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Proceedings Paper

Photosensitization Of Model Membranes By HPD: Implications For Photodynamic Therapy
Author(s): Leonard I. Grossweiner
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Paper Abstract

The photosensitizing properties of hematoporphyrin derivative (HPD) have been investigated using egg phosphatidylcholine liposomes and resealed bovine erythrocyte membranes (ghosts) as model membranes. The results demonstrate that incorporated HPD photosensitizes lipid peroxidation in liposome and ghost membranes and protein cross-linking in ghosts via the Type 2, singlet oxygen mechanism.

Paper Details

Date Published: 10 March 1987
PDF: 5 pages
Proc. SPIE 0712, Lasers in Medicine, (10 March 1987); doi: 10.1117/12.937332
Show Author Affiliations
Leonard I. Grossweiner, Illinois Institute of Technology (United States)


Published in SPIE Proceedings Vol. 0712:
Lasers in Medicine
Stephen N. Joffe; John A. Parrish, Editor(s)

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