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Proceedings Paper

Tissue Characterization Using Energy-Selective Computed Tomography
Author(s): Robert E. Alvarez; William H. Marshall; Roger Lewis
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Paper Abstract

Energy-selective computed tomography has several important properties useful for in-vivo tissue characterization. Most importantly, it produces more information than conventional computed tomography. This information can be considered to be an added dimension which can be used to eliminate the ambiguities in conventional CT data. The noise in energy-selective computed tomography is also two dimensional and an un-correlated coordinate system can be defined which is needed for studying the capabilities of the technique for characterizing tissues. By using the calibration material basis set, the information from energy-selective CT can be extracted with extreme accuracy. Our preliminary experiments indicate that the technique is accurate enough to characterize the difference between gray and white matter. Most conventional systems have difficulty in distinguishing these materials, much less characterizing the reason for their differing attenuation. Thus energy-selective CT has the promise of providing extremely accurate tissue characterization based on its physical properties.

Paper Details

Date Published: 16 July 1981
PDF: 7 pages
Proc. SPIE 0273, Application of Optical Instrumentation in Medicine IX, (16 July 1981); doi: 10.1117/12.931817
Show Author Affiliations
Robert E. Alvarez, Stanford University (United States)
William H. Marshall, Stanford University (United States)
Roger Lewis, Stanford University (United States)


Published in SPIE Proceedings Vol. 0273:
Application of Optical Instrumentation in Medicine IX
James A. Mulvaney; Joel E. Gray; Arthur G. Haus; William S. Properzio, Editor(s)

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