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Proceedings Paper

Directing growth cones of optic axons growing with laser scissors and laser tweezers
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Paper Abstract

We have combined a laser scissors and a laser tweezers to study, (1) the response of nerve fiber growth cones to laser-induced damage on single axons, and (2) localized microfluidic flow generated by laser-driven spinning birefringent particles. In the laser scissors study, sub-axotomy damage elicits a growth cone response whether damage is on the same or an adjacent axon. In laser tweezers study, the axon growth cones turn in response to the optically driven microfluidic flow. In summary, both the laser scissors and the laser tweezers studies elicit growth cone turning responses.o

Paper Details

Date Published: 10 October 2012
PDF: 6 pages
Proc. SPIE 8458, Optical Trapping and Optical Micromanipulation IX, 84580P (10 October 2012); doi: 10.1117/12.930411
Show Author Affiliations
Tao Wu, Beckman Laser Institute and Medical Clinic, Univ. of California, Irvine (United States)
Harvard Medical School and Wellman Ctr. for Photomedicine (United States)
Timo A. Nieminen, The Univ. of Queensland (Australia)
Samarendra Mohanty, Beckman Laser Institute and Medical Clinic, Univ. of California, Irvine (United States)
Jill Miotke, Univ. of California, Irvine (United States)
Ronald L. Meyer, Univ. of California, Irvine (United States)
Halina Rubinsztein-Dunlop, The Univ. of Queensland (Australia)
Michael W. Berns, Beckman Laser Institute and Medical Clinic, Univ. of California, Irvine (United States)
Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 8458:
Optical Trapping and Optical Micromanipulation IX
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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