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Proceedings Paper

Stereomicroscopic evaluation of the joint cartilage and bone tissue in osteoporosis
Author(s): Liliana Vasile; Rodica Torok; Bogdan Deleanu; Cristian Marchese; Adina Valeanu; Rodica Bodea
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Paper Abstract

Aim of the study. Assessment by stereomicroscopy of the severity of lesions in osteoporotic bone at both sexes and to correlate micro-and macro-bone fracture due to low bone density values with the disease evolution. Material and method: The study material consists of fragments of bone from the femoral head, vertebral bone, costal and iliac crest biopsy obtained from patients aged over 70 years, female and male, treated in the County Hospital of Timisoara, Department of Orthopedics. For the purpose of studying the samples in stereomicroscopy and trough polarized light it has been used the Olympus Microscope SZ ×7 and an Olympus camera with 2,5 × digital zoom and a 3× optical zoom in the Vest Politechnic Univesity. Results and discussions: Subchondral bone presents osteolysis associated with a osteoporotic bone transformation. Pseudocystic chondrolisis was noted in the osteoarticular cartilage, in addition with areas of hemorrhagic postfractural necrosis. The osteoporotic bone exhibits ischemic necrosis and focal hemorrhagic necrosis adjacent fracture. Microporosity pattern of the bone observed by stereomicroscopy correspond to the spongy bone osteoporosis images. Morphometry of the bone spiculi reveals length of 154.88 and 498.32 μ. In men we found a greater thickness of bone trabeculi compared with bone texture porosity in women. The subchondral bone supports and fulfills an important role in transmitting forces from the overlying articular cartilage inducing the bone resorbtion. The femoral head fracture may be the final event of many accumulated bone microcracks. Conclusions: Bone fragility depends not only of the spongy bone but also of the cortical bone properties. Osteolysis produced by loss of balance in the process of remodeling in favor of bone resorption leads to the thinning of the subchondral bone at both sexes.

Paper Details

Date Published: 8 May 2012
PDF: 8 pages
Proc. SPIE 8427, Biophotonics: Photonic Solutions for Better Health Care III, 84273Y (8 May 2012); doi: 10.1117/12.923061
Show Author Affiliations
Liliana Vasile, Univ. de Medicina si Farmacie Victor Babes, Timisoara (Romania)
Rodica Torok, Univ. de Vest din Timisoara (Romania)
Bogdan Deleanu, County Hospital Timisoara (Romania)
Cristian Marchese, Univ. de Medicina si Farmacie Victor Babes, Timisoara (Romania)
Adina Valeanu, Univ. de Medicina si Farmacie Victor Babes, Timisoara (Romania)
Rodica Bodea, Univ. de Medicina si Farmacie Victor Babes, Timisoara (Romania)


Published in SPIE Proceedings Vol. 8427:
Biophotonics: Photonic Solutions for Better Health Care III
Jürgen Popp; Wolfgang Drexler; Valery V. Tuchin; Dennis L. Matthews, Editor(s)

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