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Proceedings Paper

High-speed polarization-sensitive OCT at 1060 nm using a Fourier domain mode-locked swept source
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Paper Abstract

Optical coherence tomography (OCT) in the 1060nm range is interesting for in vivo imaging of the human posterior eye segment (retina, choroid, sclera), as it permits a long penetration depth. Complementary to structural images, polarization-sensitive OCT (PS-OCT) images visualize birefringent, polarization-maintaining or depolarizing areas within the sample. This information can be used to distinguish retinal layers and structures with different polarization properties. High imaging speed is crucial for imaging ocular structures in vivo in order to minimize motion artifacts while acquiring sufficiently large datasets. Here, we demonstrate PS-OCT imaging at 350 kHz A-scan rate using a two-channel PS-OCT system in conjunction with a Fourier domain mode-locked laser. The light source spectrum spans up to 100nm around the water absorption minimum at 1060 nm. By modulating the laser pump current, we can optimize the spectrum and achieve a depth resolution of 9 μm in air (6.5 μm in tissue). We acquired retinal images in vivo with high resolution and deep penetration into choroid and sclera, and features like the depolarizing RPE or an increasing phase retardation at the chorio-scleral interface are clearly visualized.

Paper Details

Date Published: 8 May 2012
PDF: 6 pages
Proc. SPIE 8427, Biophotonics: Photonic Solutions for Better Health Care III, 84271D (8 May 2012); doi: 10.1117/12.922313
Show Author Affiliations
Sebastian Marschall, Technical Univ. of Denmark (Denmark)
Teresa Torzicky, Medizinische Univ. Wien (Austria)
Thomas Klein, Ludwig-Maximilians-Univ. München (Germany)
Wolfgang Wieser, Ludwig-Maximilians-Univ. München (Germany)
Michael Pircher, Medizinische Univ. Wien (Austria)
Erich Götzinger, Medizinische Univ. Wien (Austria)
Stefan Zotter, Medizinische Univ. Wien (Austria)
Marco Bonesi, Medizinische Univ. Wien (Austria)
Benjamin Biedermann, Ludwig-Maximilians-Univ. München (Germany)
Christian Pedersen, Technical Univ. of Denmark (Denmark)
Robert Huber, Ludwig-Maximilians-Univ. München (Germany)
Christoph Hitzenberger, Medizinische Univ. Wien (Austria)
Peter Andersen, Technical Univ. of Denmark (Denmark)


Published in SPIE Proceedings Vol. 8427:
Biophotonics: Photonic Solutions for Better Health Care III
Jürgen Popp; Wolfgang Drexler; Valery V. Tuchin; Dennis L. Matthews, Editor(s)

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