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Proceedings Paper

Design of a novel pump for bio-applications
Author(s): Sheng-Li Chang; Kuo-Chi Chiu; Fu-Yuan Hsu; Jhewn-Kuang Chen
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Paper Abstract

Fluid driven devices have been widely used in many applications, such as pumping, circulating, and cooling systems in handling liquid. Their driving conditions are highly dependent on the operation purposes. Some of them work with high pressure and high flow rate without the need of flow stability. On the other hand, the steady flow with low pressure and flow rate is required for bio-applications. In a perfusion system for culturing cells, a suitable shear stress from a cultivated fluid is one of key factors to reproduce the fluid conditions of cells in a living organism. A special pump is needed to provide a steady flow rate and stress in such system. In this study, a novel design of the pump constituted by a housing and a screw-type rotor with micro-channels was proposed. To understand the flow phenomena in this design, both computational modeling and real experiment are utilized. In the experiment, a minimum rotational speed is needed to drive the fluid flow. In the modeling, the steady state with low pulsation was achieved within a short period of time. A perfusion system with 7.8% variation in flow rate could be obtained in comparison with traditional peristaltic pump with up to 29% variation in flow rate. Steady fluid flow for a perfusion system then could be obtained in this screw-type pump.

Paper Details

Date Published: 8 May 2012
PDF: 7 pages
Proc. SPIE 8428, Micro-Optics 2012, 84281F (8 May 2012); doi: 10.1117/12.921756
Show Author Affiliations
Sheng-Li Chang, Industrial Technology Research Institute (Taiwan)
Kuo-Chi Chiu, Industrial Technology Research Institute (Taiwan)
Fu-Yuan Hsu, National United Univ. (Taiwan)
Jhewn-Kuang Chen, National Taipei Univ. of Technology (Taiwan)


Published in SPIE Proceedings Vol. 8428:
Micro-Optics 2012
Hugo Thienpont; Jürgen Mohr; Hans Zappe; Hirochika Nakajima, Editor(s)

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