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Proceedings Paper

Optical trapping detects colored noise in the fluctuations of an extended DNA molecule
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Paper Abstract

We studied fluctuations of an optically trapped bead connected to a single DNA molecule anchored between the bead and a cover glass or between two optically trapped beads. Power spectral densities of the bead position for different extensions of the molecule were compared with the power spectral density of the position fluctuations of the same bead without the molecule attached. Experiments showed that the fluctuations of the DNA molecule extended up to 80% by a force of 3 pN include the colored noise contribution with spectral dependence 1/fα with α~ 0.75.

Paper Details

Date Published: 8 May 2012
PDF: 11 pages
Proc. SPIE 8427, Biophotonics: Photonic Solutions for Better Health Care III, 84270V (8 May 2012); doi: 10.1117/12.921354
Show Author Affiliations
Ignacio A. Martínez, ICFO - Institut de Ciencies Fotòniques (Spain)
Saurabh Raj, ICFO - Institut de Ciencies Fotòniques (Spain)
Dmitri Petrov, ICFO - Institut de Ciències Fotòniques (Spain)
Institució Catalana de Recerca i Estudis Avançats (Spain)

Published in SPIE Proceedings Vol. 8427:
Biophotonics: Photonic Solutions for Better Health Care III
Jürgen Popp; Wolfgang Drexler; Valery V. Tuchin; Dennis L. Matthews, Editor(s)

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