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Proceedings Paper

Surface-enhanced Raman spectroscopy of creatinine in silver colloid
Author(s): Yue Wang; Jiesi Chen; Yanan Wu; Yanping Chen; Jianji Pan; Jinping Lei; Yongjian Chen; Liqing Sun; Shangyuan Feng; Rong Chen
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Paper Abstract

Surface enhanced Raman spectroscopy (SERS) technology has already made great progress in bio-molecule detection. It can make the target molecules strongly absorbed onto the surface of metal nanoparticles, and then the Raman signal of its own has been greatly enhanced through physical and chemical enhancement mechanisms. We report the SERS spectra of creatinine in silver colloid, and study the silver colloid enhanced effects on the Raman scattering of creatinine. We can also find that creatinine concentration is linearly related to its SERS peak intensity and the detection limit of creatinine silver sol is found to be 10 mg/dl. In conclusion, we can observe that the silver colloid has very good enhanced effects for the creatinine. The potential applications of SERS in quantitative measurement of the creatinine liquor are demonstrated. The result shows that the SERS approach would provide a unique and fast test method for creatinine detection.

Paper Details

Date Published: 14 March 2012
PDF: 7 pages
Proc. SPIE 8329, Tenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011), 83290K (14 March 2012); doi: 10.1117/12.918990
Show Author Affiliations
Yue Wang, Fujian Normal Univ. (China)
Jiesi Chen, Fujian Normal Univ. (China)
Yanan Wu, Fujian Provincial Hospital (China)
Yanping Chen, Fujian Medical Univ. Teaching Hospital (China)
Fujian Provincial Tumor Hospital (China)
Jianji Pan, Fujian Medical Univ. Teaching Hospital (China)
Fujian Provincial Tumor Hospital (China)
Jinping Lei, Fujian Normal Univ. (China)
Yongjian Chen, Fujian Normal Univ. (China)
Liqing Sun, Fuzhou First Hospital (China)
Shangyuan Feng, Fujian Normal Univ. (China)
Rong Chen, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 8329:
Tenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011)

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