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Proceedings Paper

Development and investigation of flexible polymer neural probe for chronic neural recording
Author(s): Courtney Smith; Kyo D. Song; Hargsoon Yoon; Woong-Ki Kim; Tao Zeng; Larry D. Sanford
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Paper Abstract

Neural recording through microelectrodes requires biocompatibility and long term chronic usage. With a potential for various applications and effort to improve the performance of neural recording probes, consideration is taken to the tissue and cellular effects in these device designs. The degeneration of neurons due to brain tissue motion is an issue along with brain tissue inflammation in the insertion of the probes. To account for motion and irritation the material structure of the probes must be improved upon. This research presents the fabrication of neural probes on the microscale utilizing flexible polymers. Polyimide neural probes have been considered possibly to reduce degradation in their variability caused by brain motion. The microfabrication of the polyimide neural probe has an increased flexibility while accounting for biocompatibility and the needs for chronic use. Through microfabrication processes a needle probe is produced and tested for neural recording.

Paper Details

Date Published: 30 March 2012
PDF: 6 pages
Proc. SPIE 8344, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2012, 834404 (30 March 2012); doi: 10.1117/12.917481
Show Author Affiliations
Courtney Smith, Norfolk State Univ. (United States)
Kyo D. Song, Norfolk State Univ. (United States)
Hargsoon Yoon, Norfolk State Univ. (United States)
Woong-Ki Kim, Eastern Virginia Medical School (United States)
Tao Zeng, Eastern Virginia Medical School (United States)
Larry D. Sanford, Eastern Virginia Medical School (United States)

Published in SPIE Proceedings Vol. 8344:
Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2012
Vijay K. Varadan, Editor(s)

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