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Proceedings Paper

VIS-NIR spectrum analysis for distinguishing tumor and normal human breast tissue
Author(s): Yang Zhang; Yuan Yu; Valery V. Tuchin; Yongjun Chen; Xiang Wen; Caihua Liu; Jing Wang; Xingbo Xue; Dan Zhu
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Paper Abstract

The high incidence and mortality of breast cancer require an effective method for early breast diagnosis. In order to investigate the optical differences among malignant tumor, benign tumor and normal human breast tissue, a commercial spectrophotometer combined with single integrating sphere was used to measure the optical properties of different types of breast tissue in the wavelength range of 400 nm to 2200 nm in vitro. The hematoxylin and eosin staining (H&E staining) are used as the standard, and to find the find possible optical markers from the corresponding absorption or scattering spectra. This work is not only used for in vitro rapid optical diagnosis, but very helpful to develop innovative optical diagnosis of breast tumor in vivo.

Paper Details

Date Published: 9 February 2012
PDF: 6 pages
Proc. SPIE 8222, Dynamics and Fluctuations in Biomedical Photonics IX, 82221C (9 February 2012); doi: 10.1117/12.914760
Show Author Affiliations
Yang Zhang, Huazhong Univ. of Science and Technology (China)
Yuan Yu, Affiliated Tongji Hospital, Huazhong Univ. of Science and Technology (China)
Valery V. Tuchin, N.G. Chernyshevsky Saratov State Univ. (Russian Federation)
Yongjun Chen, Affiliated Tongji Hospital, Huazhong Univ. of Science and Technology (China)
Xiang Wen, Huazhong Univ. of Science and Technology (China)
Caihua Liu, Huazhong Univ. of Science and Technology (China)
Jing Wang, Huazhong Univ. of Science and Technology (China)
Xingbo Xue, Affiliated Tongji Hospital, Huazhong Univ. of Science and Technology (China); (China)
Dan Zhu, Huazhong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 8222:
Dynamics and Fluctuations in Biomedical Photonics IX
Valery V. Tuchin; Donald D. Duncan; Kirill V. Larin; Martin J. Leahy; Ruikang K. Wang, Editor(s)

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