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Proceedings Paper

Comparison of relative pressures calculated from PC-MRI and SPIV with catheter-based pressure measurements in a stenotic phantom model
Author(s): Iman Khodarahmi; Mostafa Shakeri; Melanie Kotys-Traughber; Michael K. Sharp; Amir A. Amini
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Paper Abstract

This paper describes an experimental system for validation of an approach to non-invasive determination of pressure gradients in stenotic flows as encountered in peripheral arterial disease. Pressure gradient across a Gaussian-shaped 87% area stenosis phantom was estimated by solving the pressure Poisson equation (PPE) for a steady flow mimicking the blood flow through the human iliac artery. The velocity field needed to solve the pressure equation was obtained using Phase-Contrast MRI (PC-MRI) and Stereoscopic Particle Image Velocimetry (SPIV). Steady flow rate of 46.9 ml/s was used, which corresponds to a Reynolds number of 188 and 595 at the inlet and stenosis throat, respectively (in the range of mean Reynolds number encountered, in-vivo). Results of PC-MRI and SPIV have been compared to the pressures measured directly by a pressure catheter transducer. The reconstructed pressure drop along the centerline overestimates the catheter reference pressure drop by 8.5% and 10.5% for PC_MRI and SPIV methods, respectively.

Paper Details

Date Published: 18 April 2012
PDF: 7 pages
Proc. SPIE 8317, Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging, 83170E (18 April 2012); doi: 10.1117/12.914716
Show Author Affiliations
Iman Khodarahmi, Medical Imaging Lab., Univ. of Louisville (United States)
Mostafa Shakeri, Medical Imaging Lab., Univ. of Louisville (United States)
Biofluid Mechanics Lab., Univ. of Louisville (United States)
Melanie Kotys-Traughber, Philips Healthcare (United States)
Michael K. Sharp, Biofluid Mechanics Lab., Univ. of Louisville (United States)
Amir A. Amini, Medical Imaging Lab., Univ. of Louisville (United States)


Published in SPIE Proceedings Vol. 8317:
Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging
Robert C. Molthen; John B. Weaver, Editor(s)

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