Share Email Print

Proceedings Paper

Bioinformatics analysis and characteristics of VP23 encoded by the newly identified UL18 gene of duck enteritis virus
Author(s): Xiwen Chen; Anchun Cheng; Mingshu Wang; Jun Xiang
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

In this study, the predicted information about structures and functions of VP23 encoded by the newly identified DEV UL18 gene through bioinformatics softwares and tools. The DEV UL18 was predicted to encode a polypeptide with 322 amino acids, termed VP23, with a putative molecular mass of 35.250 kDa and a predicted isoelectric point (PI) of 8.37, no signal peptide and transmembrane domain in the polypeptide. The prediction of subcellular localization showed that the DEV-VP23 located at endoplasmic reticulum with 33.3%, mitochondrial with 22.2%, extracellular, including cell wall with 11.1%, vesicles of secretory system with 11.1%, Golgi with 11.1%, and plasma membrane with 11.1%. The acid sequence of analysis showed that the potential antigenic epitopes are situated in 45-47, 53-60, 102-105, 173-180, 185-189, 260-265, 267-271, and 292-299 amino acids. All the consequences inevitably provide some insights for further research about the DEV-VP23 and also provide a fundament for further study on the the new type clinical diagnosis of DEV and can be used for the development of new DEV vaccine.

Paper Details

Date Published: 1 October 2011
PDF: 9 pages
Proc. SPIE 8285, International Conference on Graphic and Image Processing (ICGIP 2011), 82857R (1 October 2011); doi: 10.1117/12.913537
Show Author Affiliations
Xiwen Chen, Mianyang Normal Univ. (China)
Anchun Cheng, Sichuan Agricultural Univ. (China)
Mingshu Wang, Sichuan Agricultural Univ. (China)
Jun Xiang, Sichuan Agricultural Univ. (China)

Published in SPIE Proceedings Vol. 8285:
International Conference on Graphic and Image Processing (ICGIP 2011)
Yi Xie; Yanjun Zheng, Editor(s)

© SPIE. Terms of Use
Back to Top