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Proceedings Paper

Miniaturized neural interfaces and implants
Author(s): Thomas Stieglitz; Tim Boretius; Juan Ordonez; Christina Hassler; Christian Henle; Wolfgang Meier; Dennis T. T. Plachta; Martin Schuettler
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Paper Abstract

Neural prostheses are technical systems that interface nerves to treat the symptoms of neurological diseases and to restore sensory of motor functions of the body. Success stories have been written with the cochlear implant to restore hearing, with spinal cord stimulators to treat chronic pain as well as urge incontinence, and with deep brain stimulators in patients suffering from Parkinson's disease. Highly complex neural implants for novel medical applications can be miniaturized either by means of precision mechanics technologies using known and established materials for electrodes, cables, and hermetic packages or by applying microsystems technologies. Examples for both approaches will be introduced and discussed. Electrode arrays for recording of electrocorticograms during presurgical epilepsy diagnosis have been manufactured using approved materials and a marking laser to achieve an integration density that is adequate in the context of brain machine interfaces, e.g. on the motor cortex. Microtechnologies have to be used for further miniaturization to develop polymer-based flexible and light weighted electrode arrays to interface the peripheral and central nervous system. Polyimide as substrate and insulation material will be discussed as well as several application examples for nerve interfaces like cuffs, filament like electrodes and large arrays for subdural implantation.

Paper Details

Date Published: 14 February 2012
PDF: 12 pages
Proc. SPIE 8251, Microfluidics, BioMEMS, and Medical Microsystems X, 82510A (14 February 2012); doi: 10.1117/12.912526
Show Author Affiliations
Thomas Stieglitz, Albert-Ludwigs-Univ. Freiburg (Germany)
Tim Boretius, Albert-Ludwigs-Univ. Freiburg (Germany)
Juan Ordonez, Albert-Ludwigs-Univ. Freiburg (Germany)
Christina Hassler, Albert-Ludwigs-Univ. Freiburg (Germany)
Christian Henle, Albert-Ludwigs-Univ. Freiburg (Germany)
CorTec GmbH (Germany)
Wolfgang Meier, Albert-Ludwigs-Univ. Freiburg (Germany)
CorTec GmbH (Germany)
Dennis T. T. Plachta, Albert-Ludwigs-Univ. Freiburg (Germany)
Martin Schuettler, Albert-Ludwigs-Univ. Freiburg (Germany)

Published in SPIE Proceedings Vol. 8251:
Microfluidics, BioMEMS, and Medical Microsystems X
Holger Becker; Bonnie L. Gray, Editor(s)

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