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Proceedings Paper

Role of iNOS gene expression in the anti-inflammatory and tissue protective mechanisms of continuous wave at 630-905nm and 905nm superpulsed laser therapy
Author(s): Arkady Mandel; Yumi Moriyama; Jamie Fong; Roger Dumoulin-White; Lothar Lilge
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Paper Abstract

Up regulation of iNOS gene expression is playing a role in the initiation of the anti-inflammatory and tissue protective mechanisms related to nitric oxide (NO) for continuous wave red and infrared as well as 905nm superpulsed laser therapy (SPLT). The iNOS expression before and after laser therapy was evaluated in a zymosan-induced acute arthritis model, in knee joints of young (<15 weeks), middle aged (>15 weeks and < 35 weeks) and old (> 35 weeks) FVB/N-Tg (iNOS-luc) mice by bioluminescence imaging.

Paper Details

Date Published: 10 March 2012
PDF: 9 pages
Proc. SPIE 8211, Mechanisms for Low-Light Therapy VII, 82110E (10 March 2012); doi: 10.1117/12.912200
Show Author Affiliations
Arkady Mandel, Theralase, Inc. (Canada)
Yumi Moriyama, Ontario Cancer Institute (Canada)
Univ. of Toronto (Canada)
Jamie Fong, Theralase, Inc. (Canada)
Roger Dumoulin-White, Theralase, Inc. (Canada)
Lothar Lilge, Ontario Cancer Institute (Canada)
Univ. of Toronto (Canada)


Published in SPIE Proceedings Vol. 8211:
Mechanisms for Low-Light Therapy VII
Michael R. Hamblin; Juanita Anders; James D. Carroll, Editor(s)

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