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Proceedings Paper

Contrast-to-noise ratio improvement in volume-of-interest cone beam breast CT
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Paper Abstract

In this study, we demonstrated the contrast-to-noise ratio (CNR) improvement in breast cone beam CT (CBCT) using the volume-of-interest (VOI) scanning technique. In VOI breast CBCT, the breast is first scanned at a low exposure level. A pre-selected VOI is then scanned at a higher exposure level with collimated x-rays. The two image sets are combined together to reconstruct high quality 3-D images of the VOI. A flat panel detector based system was built to demonstrate and investigate the CNR improvement in VOI breast CBCT. The CNRs of the 8 plastic cones (Teflon, Delrin, polycarbonate, Lucite, solid water, high density polystyrene, nylon and polystyrene) in a breast phantom were measured in images obtained with the VOI CBCT technique and compared to those measured in standard full field CBCT images. CNRs in VOI CBCT images were found to be higher than those in regular CBCT images in all plastic cones. The mean glandular doses (MGDs) from the combination of a high exposure VOI scan and a low exposure full-field scan was estimated to be similar to that from regular full-field scan at standard exposure level. The VOI CBCT technique allows a VOI to be imaged with enhanced image quality with an MGD similar to that from regular CBCT technique.

Paper Details

Date Published: 3 March 2012
PDF: 7 pages
Proc. SPIE 8313, Medical Imaging 2012: Physics of Medical Imaging, 83134X (3 March 2012); doi: 10.1117/12.911932
Show Author Affiliations
Youtao Shen, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Xinming Liu, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Chao-Jen Lai, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Yuncheng Zhong, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Ying Yi, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Zhicheng You, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Tianpeng Wang, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Chris C. Shaw, The Univ. of Texas M.D. Anderson Cancer Ctr. (United States)


Published in SPIE Proceedings Vol. 8313:
Medical Imaging 2012: Physics of Medical Imaging
Norbert J. Pelc; Robert M. Nishikawa; Bruce R. Whiting, Editor(s)

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