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Proceedings Paper

Computerized scheme for lung nodule detection in multi-projection chest radiography
Author(s): Wei Guo; Qiang Li; Sarah J. Boyce; H. Page McAdams; Junji Shiraishi; Kunio Doi; Ehsan Samei
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Paper Abstract

Our purposes are to develop a conventional computer-aided diagnostic (CAD) scheme and a new fusion CAD scheme for the detection of lung nodules in multi-projection chest radiography, and to verify that information fused from the multi-projection chest radiography can greatly improve the performance of the conventional CAD scheme. The conventional CAD scheme processed each of the three projection images of a subject independently, and discarded the correlation information between the three images. The fusion CAD scheme registered all candidates detected by the conventional CAD scheme in the three images of a subject, and integrated the correlation information between the registered candidates to remove false positives. The CAD schemes were trained and evaluated on a database with 97 subjects. At the sensitivities of 70%, 65% and 60%, the conventional CAD scheme reported 20.4, 13.6 and 8.8 false positives per image, respectively, whereas the fusion CAD scheme reported 4.5, 2.8 and 1.2 false positives per image, respectively. The fusion of correlation information can markedly improve the performance of CAD scheme for lung nodule detection.

Paper Details

Date Published: 14 April 2012
PDF: 6 pages
Proc. SPIE 8315, Medical Imaging 2012: Computer-Aided Diagnosis, 83150T (14 April 2012); doi: 10.1117/12.911881
Show Author Affiliations
Wei Guo, Duke Univ. Medical Ctr. (United States)
Qiang Li, Duke Univ. Medical Ctr. (United States)
Sarah J. Boyce, Duke Univ. Medical Ctr. (United States)
Univ. of North Carolina (United States)
H. Page McAdams, Duke Univ. Medical Ctr. (United States)
Junji Shiraishi, Kumamoto Univ. (Japan)
Kunio Doi, Kurt Rossmann Labs. for Radiologic Image Research, The Univ. of Chicago (United States)
Ehsan Samei, Duke Univ. Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 8315:
Medical Imaging 2012: Computer-Aided Diagnosis
Bram van Ginneken; Carol L. Novak, Editor(s)

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