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Proceedings Paper

Automated artery-venous classification of retinal blood vessels based on structural mapping method
Author(s): Vinayak S. Joshi; Mona K. Garvin; Joseph M. Reinhardt; Michael D. Abramoff
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Paper Abstract

Retinal blood vessels show morphologic modifications in response to various retinopathies. However, the specific responses exhibited by arteries and veins may provide a precise diagnostic information, i.e., a diabetic retinopathy may be detected more accurately with the venous dilatation instead of average vessel dilatation. In order to analyze the vessel type specific morphologic modifications, the classification of a vessel network into arteries and veins is required. We previously described a method for identification and separation of retinal vessel trees; i.e. structural mapping. Therefore, we propose the artery-venous classification based on structural mapping and identification of color properties prominent to the vessel types. The mean and standard deviation of each of green channel intensity and hue channel intensity are analyzed in a region of interest around each centerline pixel of a vessel. Using the vector of color properties extracted from each centerline pixel, it is classified into one of the two clusters (artery and vein), obtained by the fuzzy-C-means clustering. According to the proportion of clustered centerline pixels in a particular vessel, and utilizing the artery-venous crossing property of retinal vessels, each vessel is assigned a label of an artery or a vein. The classification results are compared with the manually annotated ground truth (gold standard). We applied the proposed method to a dataset of 15 retinal color fundus images resulting in an accuracy of 88.28% correctly classified vessel pixels. The automated classification results match well with the gold standard suggesting its potential in artery-venous classification and the respective morphology analysis.

Paper Details

Date Published: 23 February 2012
PDF: 8 pages
Proc. SPIE 8315, Medical Imaging 2012: Computer-Aided Diagnosis, 83151C (23 February 2012); doi: 10.1117/12.911490
Show Author Affiliations
Vinayak S. Joshi, The Univ. of Iowa (United States)
Mona K. Garvin, The Univ. of Iowa (United States)
Iowa City VA Health Care System (United States)
Joseph M. Reinhardt, The Univ. of Iowa (United States)
Michael D. Abramoff, The Univ. of Iowa (United States)

Published in SPIE Proceedings Vol. 8315:
Medical Imaging 2012: Computer-Aided Diagnosis
Bram van Ginneken; Carol L. Novak, Editor(s)

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