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Proceedings Paper

Tractography of white matter based on diffusion tensor imaging in ischaemic stroke involving the corticospinal tract: a preliminary study
Author(s): Chongguang Zhong; Lijun Bai; Fangyuan Cui; Ruwei Dai; Ting Xue; Hu Wang; Wenjuan Wei; Zhenyu Liu; Youbo You; Yihuai Zou; Jie Tian
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Paper Abstract

Diffusion tensor MR imaging (DTI) provides information on diffusion anisotropy in vivo, which can be exhibited three-dimensional white matter tractography. Five healthy volunteers and five right-hand affected patients with early subacute ischaemic infarction involving the posterior limb of the internal capsule or corona radiate were recruited in this study. We used 3D white matter tractography to show the corticospinal tract in both volunteer group and stroke group. Then we compared parameters of the corticospinal tract in patients with that in normal subjects and assessed the relationships between the fiber number of the corticospinal tract in ipsilesional hemisphere and indicators of the patients' rehabilitation using Pearson correlation analysis. The fractional anisotropy (FA) values and apparent diffusion coefficient (ADC) values in the ipsilesional corticospinal tract may significantly reduce comparing with the volunteer group. In addition, the stroke patient with less fiber number of the ipsilesional corticospinal tract may bear more possibilities of better motor rehabilitation. The FA values, ADC values and fiber number of the corticospinal tract in the ipsilesional hemisphere might be helpful to the prognosis and prediction of clinical treatment in stroke patients.

Paper Details

Date Published: 12 April 2012
PDF: 8 pages
Proc. SPIE 8317, Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging, 831708 (12 April 2012); doi: 10.1117/12.911393
Show Author Affiliations
Chongguang Zhong, Intelligent Medical Research Ctr., Institute of Automation (China)
Lijun Bai, Intelligent Medical Research Ctr., Institute of Automation (China)
Fangyuan Cui, Dongzhimen Hospital, Beijing Univ. of Chinese Medicine (China)
Ruwei Dai, Intelligent Medical Research Ctr., Institute of Automation (China)
Ting Xue, Life Sciences Research Ctr., Xidian Univ. (China)
Hu Wang, Intelligent Medical Research Ctr., Institute of Automation (China)
Wenjuan Wei, Intelligent Medical Research Ctr., Institute of Automation (China)
Zhenyu Liu, Intelligent Medical Research Ctr., Institute of Automation (China)
Youbo You, Intelligent Medical Research Ctr., Institute of Automation (China)
Yihuai Zou, Beijing Univ. of Chinese Medicine (China)
Jie Tian, Intelligent Medical Research Ctr., Institute of Automation (China)
Life Sciences Research Ctr., Xidian Univ. (China)


Published in SPIE Proceedings Vol. 8317:
Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging
Robert C. Molthen; John B. Weaver, Editor(s)

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