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Proceedings Paper

In vivo human retinal and choroidal vasculature visualization using differential phase contrast swept source optical coherence tomography at 1060 nm
Author(s): Reza Motaghiannezam; Scott Fraser
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Paper Abstract

A differential phase contrast (DPC) method is validated for in vivo human retinal and choroidal vasculature visualization using high-speed swept-source optical coherence tomography (SS-OCT) at 1060 nm. The vasculature was identified as regions of motion by creating differential phase variance (DPV) tomograms: multiple B-scans were collected of individual slices through the retina and the variance of the phase differences was calculated. DPV captured the small vessels and the meshwork of capillaries associated with the inner retina in en face images over 4 mm2 in a normal subject. En face DPV images were capable of capturing the microvasculature and regions of motion through the inner retina and choroid.

Paper Details

Date Published: 30 January 2012
PDF: 7 pages
Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 821304 (30 January 2012); doi: 10.1117/12.910991
Show Author Affiliations
Reza Motaghiannezam, California Institute of Technology (United States)
Scott Fraser, California Institute of Technology (United States)


Published in SPIE Proceedings Vol. 8213:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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