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Proceedings Paper

Small-animal tomography with a liquid-metal-jet x-ray source
Author(s): D. H. Larsson; U. Lundström; U. Westermark; P. A. C. Takman; A. Burvall; M. Arsenian Henriksson; H. M. Hertz
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Paper Abstract

X-ray tomography of small animals is an important tool for medical research. For high-resolution x-ray imaging of few-cm-thick samples such as, e.g., mice, high-brightness x-ray sources with energies in the few-10-keV range are required. In this paper we perform the first small-animal imaging and tomography experiments using liquid-metal-jet-anode x-ray sources. This type of source shows promise to increase the brightness of microfocus x-ray systems, but present sources are typically optimized for an energy of 9 keV. Here we describe the details of a high-brightness 24-keV electron-impact laboratory microfocus x-ray source based on continuous operation of a heated liquid-In/Ga-jet anode. The source normally operates with 40 W of electron-beam power focused onto the metal jet, producing a 7×7 μm2 FWHM x-ray spot. The peak spectral brightness is 4 × 109 photons / ( s × mm2 × mrad2 × 0.1%BW) at the 24.2 keV In Kα line. We use the new In/Ga source and an existing Ga/In/Sn source for high-resolution imaging and tomography of mice.

Paper Details

Date Published: 8 March 2012
PDF: 7 pages
Proc. SPIE 8313, Medical Imaging 2012: Physics of Medical Imaging, 83130N (8 March 2012); doi: 10.1117/12.910777
Show Author Affiliations
D. H. Larsson, Royal Institute of Technology (Sweden)
U. Lundström, Royal Institute of Technology (Sweden)
U. Westermark, Karolinska Institutet (Sweden)
P. A. C. Takman, Royal Institute of Technology (Sweden)
A. Burvall, Royal Institute of Technology (Sweden)
M. Arsenian Henriksson, Karolinska Institutet (Sweden)
H. M. Hertz, Royal Institute of Technology (Sweden)

Published in SPIE Proceedings Vol. 8313:
Medical Imaging 2012: Physics of Medical Imaging
Norbert J. Pelc; Robert M. Nishikawa; Bruce R. Whiting, Editor(s)

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