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Proceedings Paper

Combination of Stokes polarized light imaging, roughness metrics and morphological features for the detection of melanoma
Author(s): P. Ghassemi; J. W. Shupp; S. Venna; M. E. Boisvert; K. E. Flanagan; M. H. Jordan; J. C. Ramella-Roman
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Paper Abstract

Skin cancer is the most common and most rapidly increasing form of cancer in the world. Optimal treatment of skin cancer before it reaches metastasis depends critically on early diagnosis. Usually physicians will measure some outward features to diagnose malignancy of pigmented skin lesion. These are mostly morphological features like border irregularity, size, shape, and color. Valuable information can be obtained from the analysis of skin roughness. Previously, we developed a hemispherical imaging Stokes polarimeter to monitor skin cancer based on a roughness assessment of the epidermis. In this study, Stokes images were analyzed to measure polarization properties of skin samples such as the principal angle of the polarization ellipse and the degree of polarization. A processing algorithm based on morphological operators was also developed and applied on Stokes images to extract shape information. Finally, an appropriate classifier was designed to determine the type of lesion based on morphological features as well as the roughness information. Clinical evaluation of the technique was performed on patients with benign nevi, melanocytic nevi, melanoma, and normal skin.

Paper Details

Date Published: 9 February 2012
PDF: 6 pages
Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 82070H (9 February 2012); doi: 10.1117/12.910534
Show Author Affiliations
P. Ghassemi, The Catholic Univ. of America (United States)
J. W. Shupp, The Catholic Univ. of America (United States)
MedStar Health Research Institute (United States)
S. Venna, MedStar Health Research Institute (United States)
M. E. Boisvert, MedStar Health Research Institute (United States)
K. E. Flanagan, MedStar Health Research Institute (United States)
M. H. Jordan, MedStar Health Research Institute (United States)
J. C. Ramella-Roman, The Catholic Univ. of America (United States)


Published in SPIE Proceedings Vol. 8207:
Photonic Therapeutics and Diagnostics VIII
Anita Mahadevan-Jansen; Andreas Mandelis; Kenton W. Gregory; Nikiforos Kollias; Hyun Wook Kang; Henry Hirschberg; Melissa J. Suter; Brian Jet-Fei Wong; Justus F. Ilgner; Stephen Lam; Bodo E. Knudsen; Steen Madsen; E. Duco Jansen; Bernard Choi; Guillermo J. Tearney; Laura Marcu; Haishan Zeng; Matthew Brenner; Krzysztof Izdebski, Editor(s)

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