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Proceedings Paper

Frequency domain photoacoustic correlation (radar) imaging: a novel methodology for non-invasive imaging of biological tissues
Author(s): Sergey A. Telenkov; Rudolf Alwi; Andreas Mandelis; Willa Shi; Emily Chen; Alex I. Vitkin
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Paper Abstract

We report the development of a novel frequency-domain biomedical photoacoustic (PA) system that utilizes a continuous-wave laser source with a custom intensity modulation pattern for spatially-resolved imaging of biological tissues. The feasibility of using relatively long duration and low optical power laser sources for spatially-resolved PA imaging is presented. We demonstrate that B-mode PA imaging can be performed using an ultrasonic phased array coupled with multi-channel correlation processing and a frequency-domain beamforming algorithm. Application of the frequency-domain PA correlation methodology is shown using tissue-like phantoms with embedded optical contrast, tissue ex-vivo samples and a small animal model in-vivo.

Paper Details

Date Published: 23 February 2012
PDF: 6 pages
Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 82231J (23 February 2012); doi: 10.1117/12.909951
Show Author Affiliations
Sergey A. Telenkov, Univ. of Toronto (Canada)
Rudolf Alwi, Univ. of Toronto (Canada)
Andreas Mandelis, Univ. of Toronto (Canada)
Willa Shi, Ontario Cancer Institute (Canada)
Emily Chen, Ontario Cancer Institute (Canada)
Alex I. Vitkin, Ontario Cancer Institute (Canada)

Published in SPIE Proceedings Vol. 8223:
Photons Plus Ultrasound: Imaging and Sensing 2012
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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