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Proceedings Paper

Bio optofluidics cell sorter: cell-BOCS concept and applications
Author(s): Tue Roth; Jesper Glückstad
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Paper Abstract

The cell-BOCS is a novel microfluidics based cell-sorting instrument utilizing next generation optical trapping technology developed at the Technical University of Denmark. It is targeted emerging bio-medical research and diagnostics markets where it for certain applications offers a number of advantages over conventional fluorescence activated cell-sorting (FACSTM) technology. Advantages include gentle handling of cells, sterile sorting, easy operation, small footprint and lower cost allowing out-of-core-facility use. Application examples are found within sorting of fragile transfected cells, high value samples and primary cell lines, where traditional FACS technology has limited application due to it's droplet-based approach to cell-sorting. In the diagnostics field, in particular applying the cell-BOCS for isolating pure populations of circulating tumor cells is an area that has generated a lot of interest.

Paper Details

Date Published: 10 February 2012
PDF: 6 pages
Proc. SPIE 8274, Complex Light and Optical Forces VI, 82740J (10 February 2012); doi: 10.1117/12.909783
Show Author Affiliations
Tue Roth, Technical Univ. of Denmark (Denmark)
Jesper Glückstad, Technical Univ. of Denmark (Denmark)


Published in SPIE Proceedings Vol. 8274:
Complex Light and Optical Forces VI
Enrique J. Galvez; David L. Andrews; Jesper Glückstad; Marat S. Soskin, Editor(s)

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