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Proceedings Paper

Multi angle view of lung using optical coherence tomography (OCT)
Author(s): Ali Golabchi; Charles A. DiMarzio; Andrew Gouldstone
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Paper Abstract

Lung imaging, visualization and measurement of alveolar volume has great importance in determining lung health. However, the heterogeneity of lung tissue complicates this task. In this paper multi angle Optical Coherence Tomography (OCT) is used to overcome this problem. One of the limitations of utilizing OCT in lung is the speckle noise and artifacts that originate from the refraction at the tissue-air interface inside the lung. Multi angle view of lung using OCT is incoherent summation of multiple angle-diverse images. Utilizing image registration of multi angle OCT scans of the lung helps reduce the speckle noise and refraction artifacts. This technique helps extract more information from the images which improves visualization and the ability to measure the geometry of alveoli. The other diculty of utilizing OCT is interpreting the images due to the low numerical aperture (NA) on the OCT. The multi angle view of the lung increases NA, which increase the imaging resolution through synthetic aperture imaging. In this paper in ated excised lung tissue and lung phantom are presented.

Paper Details

Date Published: 8 February 2012
PDF: 6 pages
Proc. SPIE 8227, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX, 82270X (8 February 2012); doi: 10.1117/12.909452
Show Author Affiliations
Ali Golabchi, Northeastern Univ. (United States)
Charles A. DiMarzio, Northeastern Univ. (United States)
Andrew Gouldstone, Northeastern Univ. (United States)
CenSSIS (United States)


Published in SPIE Proceedings Vol. 8227:
Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX
Jose-Angel Conchello; Carol J. Cogswell; Tony Wilson; Thomas G. Brown, Editor(s)

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