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Proceedings Paper

Integrated flexible optitrode for neural stimulation and recording
Author(s): Szu-Te Lin; John A. Dani; John C. Wolfe; Wei-Chuan Shih
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Paper Abstract

We present an integrated flexible probe for deep brain optical stimulation and electrical recording, termed as "Optitrode". This device features an annular light guide consisting of layered transparent polymer and silica, and is fabricated by a unique process we developed: V-groove guided capillary assembly (VGCA), by which a single or multiple microwires can be integrated inside the light guide with high precision. The Optitrode design promises an ultrahigh length-to-diameter ratio > 500 (5 cm long, < 100 μm diameter), enabling minimally-invasive deep brain applications. Furthermore, the highly flexible nature of Optitrode could address a current barrier in rigid brain implants with limited life-time by conforming to the brain micromotion during long-term operation.

Paper Details

Date Published: 14 February 2012
PDF: 7 pages
Proc. SPIE 8251, Microfluidics, BioMEMS, and Medical Microsystems X, 82510B (14 February 2012); doi: 10.1117/12.908994
Show Author Affiliations
Szu-Te Lin, Univ. of Houston (United States)
John A. Dani, Baylor College of Medicine (United States)
John C. Wolfe, Univ. of Houston (United States)
Wei-Chuan Shih, Univ. of Houston (United States)

Published in SPIE Proceedings Vol. 8251:
Microfluidics, BioMEMS, and Medical Microsystems X
Holger Becker; Bonnie L. Gray, Editor(s)

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