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Proceedings Paper

Accurate dosimetry for monitoring response to photodynamic therapy
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Paper Abstract

Photodynamic therapy (PDT) is becoming a treatment of choice for cancer because of its low cost, high effectiveness and low damage to healthy tissue. Successful PDT outcome depends on accurate dosimetry, which is currently lacking, leading to variable and/or ineffective treatment outcome. We report on our research and developmental efforts towards an implicit dosimetric method for PDT that will provide an accurate assessment of treatment effectiveness by continuous monitoring of the in vivo drug concentration and the oxygen concentration in tissue. This approach uses the same tools presently available for PDT, making it attractive to the health professionals without increasing treatment cost.

Paper Details

Date Published: 9 March 2012
PDF: 8 pages
Proc. SPIE 8210, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXI, 82100R (9 March 2012); doi: 10.1117/12.908836
Show Author Affiliations
M. Seetamraju, Radiation Monitoring Devices, Inc. (United States)
R. S. Gurjar, Radiation Monitoring Devices, Inc. (United States)
R. Myers, Radiation Monitoring Devices, Inc. (United States)
T. Hasan, Wellman Ctr. for Photomedicine, Massachusetts General Hospital (United States)
D. E. Wolf, Radiation Monitoring Devices, Inc. (United States)


Published in SPIE Proceedings Vol. 8210:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXI
David H. Kessel; Tayyaba Hasan, Editor(s)

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