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Proceedings Paper

A new diagnostic tool based on diffusion reflection measurements of gold nanoparticles
Author(s): Rinat Ankri; Hamootal Duadi; Dror Fixler
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Paper Abstract

The ability to quantitatively and non-invasively detect nanoparticles in tissues has important implications on their development as an in-vivo cancer diagnostic tool. The Diffusion Reflection (DR) method is a simple, non-invasive imaging technique which has been proven useful for the investigation of tissue's optical parameters. We present a new method for the measurements of the GNR concentration in tissue-like phantoms based on DR measurements and the intense light absorption of gold nanorods (GNR). Monte Carlo simulations and tissue-like phantom measurements of the reflected light intensity are presented. The ability to extract the phantoms' optical properties and the GNR concentration in it from DR measurements was demonstrated.

Paper Details

Date Published: 9 February 2012
PDF: 16 pages
Proc. SPIE 8225, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X, 82250L (9 February 2012); doi: 10.1117/12.908789
Show Author Affiliations
Rinat Ankri, Bar-Ilan Univ. (Israel)
Hamootal Duadi, Bar-Ilan Univ. (Israel)
Dror Fixler, Bar-Ilan Univ. (Israel)

Published in SPIE Proceedings Vol. 8225:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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