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Proceedings Paper

Raman spectroscopy of blood in-vitro
Author(s): A. E. Villanueva-Luna; J. Castro-Ramos; S. Vazquez-Montiel; A. Flores-Gil; C. M. Ortiz-Lima; J. A. Delgado-Atencio
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Paper Abstract

We present Raman spectra from a sample of 8 volunteers that have different type of blood. The experimental data were carried out using a 785 nm excitation laser and an ocean optics spectrometer of 6 cm-1 resolution, with a used spectral region from 1000 to 1800 cm-1. We find Raman features at 1000 and 1542 cm-1 regarded with hemoglobin and its derivatives. Also we find Raman features at 1248 and 1342 cm-1 that are now regarded with pure fibrin. In this work, we use Principal Component analysis (PCA) to determine all variations of our samples, which allows us to define a classification of the influence of the blood type. Finally, we found vibrational lines of cholesterol, glucose and triglycerides that are reported in literature.

Paper Details

Date Published: 2 February 2012
PDF: 7 pages
Proc. SPIE 8229, Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV, 82291D (2 February 2012); doi: 10.1117/12.908689
Show Author Affiliations
A. E. Villanueva-Luna, Instituto Nacional de Astrofísica, Óptica y Electrónica (Mexico)
J. Castro-Ramos, Instituto Nacional de Astrofísica, Óptica y Electrónica (Mexico)
S. Vazquez-Montiel, Instituto Nacional de Astrofísica, Óptica y Electrónica (Mexico)
A. Flores-Gil, Univ. Autónoma del Carmen (Mexico)
C. M. Ortiz-Lima, Instituto Nacional de Astrofísica, Óptica y Electrónica (Mexico)
J. A. Delgado-Atencio, Instituto Nacional de Astrofísica, Óptica y Electrónica (Mexico)


Published in SPIE Proceedings Vol. 8229:
Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV
Gerard L. Coté; Robert J. Nordstrom, Editor(s)

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