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Proceedings Paper

Radially polarized tip-enhanced near-field coherent anti-Stokes Raman scattering microscopy for bioimaging
Author(s): Jian Lin; Kenneth Er; Zhiwei Huang
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Paper Abstract

CARS is meritorious in its ability to perform chemical selective imaging, but its spatial resolution is limited by the diffraction limit of light; however, this limit can be broken by combining CARS and near-field scanning microscope. In this work, we report a novel radially polarized near-field coherent anti-Stokes Raman scattering microscopy (RP-NF-CARS), which uses radially polarized light as excitation to enhance the electric field enhancement under a metallic tip, and improves the signal to background ratio compared with that using linearly polarized excitations. We applied RP-NF-CARS to image nano-scale polystyrene beads and biological system.

Paper Details

Date Published: 2 February 2012
PDF: 6 pages
Proc. SPIE 8231, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VIII, 82310B (2 February 2012); doi: 10.1117/12.908476
Show Author Affiliations
Jian Lin, National Univ. of Singapore (Singapore)
Kenneth Er, National Univ. of Singapore (Singapore)
Zhiwei Huang, National Univ. of Singapore (Singapore)


Published in SPIE Proceedings Vol. 8231:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VIII
Alexander N. Cartwright; Dan V. Nicolau, Editor(s)

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