Share Email Print
cover

Proceedings Paper

Integration of a three-dimensional filter in a microfluidic chip for separation of microscale particles
Author(s): Nicola Bellini; Yu Gu; Lorenzo Amato; Shane Eaton; Giulio Cerullo; Roberto Osellame
Format Member Price Non-Member Price
PDF $17.00 $21.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We report on the integration of a size-based three-dimensional filter, with micrometer-sized pores, in a commercial microfluidic chip. The filter is fabricated inside an already sealed microfluidic channel using the unique capabilities of two-photon polymerization. This direct-write technique enables integration of the filter by post-processing in a chip that has been fabricated by standard technologies. The filter is located at the intersection of two channels in order to control the amount of flow passing through the filter. Tests with a suspension of 3-ìm polystyrene spheres in a Rhodamine 6G solution show that 100% of the spheres are stopped, while the fluorescent molecules are transmitted through the filter. We demonstrate operation up to a period of 25 minutes without any evidence of clogging. Moreover, the filter can be cleaned and reused by reversing the flow.

Paper Details

Date Published: 17 February 2012
PDF: 7 pages
Proc. SPIE 8244, Laser-based Micro- and Nanopackaging and Assembly VI, 82440G (17 February 2012); doi: 10.1117/12.908455
Show Author Affiliations
Nicola Bellini, Istituto di Fotonica e Nanotecnologie, CNR, Politecnico di Milano (Italy)
Yu Gu, Massachusetts Institute of Technology (United States)
Lorenzo Amato, Istituto di Fotonica e Nanotecnologie, CNR, Politecnico di Milano (Italy)
Shane Eaton, Istituto di Fotonica e Nanotecnologie, CNR, Politecnico di Milano (Italy)
Giulio Cerullo, Istituto di Fotonica e Nanotecnologie, CNR, Politecnico di Milano (Italy)
Roberto Osellame, Istituto di Fotonica e Nanotecnologie, CNR, Politecnico di Milano (Italy)


Published in SPIE Proceedings Vol. 8244:
Laser-based Micro- and Nanopackaging and Assembly VI
Friedrich G. Bachmann; Wilhelm Pfleging; Kunihiko Washio; Jun Amako; Willem Hoving; Yongfeng Lu, Editor(s)

© SPIE. Terms of Use
Back to Top