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Proceedings Paper

Multiphoton spectroscopy of human skin in vivo
Author(s): Hans G. Breunig; Martin Weinigel; Karsten König
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Paper Abstract

In vivo multiphoton-intensity images and emission spectra of human skin are reported. Optical sections from different depths of the epidermis and dermis have been measured with near-infrared laser-pulse excitation. While the intensity images reveal information on the morphology, the spectra show emission characteristics of main endogenous skin fluorophores like keratin, NAD(P)H, melanin, elastin and collagen as well as of second harmonic generation induced by the excitation-light interaction with the dermal collagen network.

Paper Details

Date Published: 13 February 2012
PDF: 5 pages
Proc. SPIE 8225, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X, 82251D (13 February 2012); doi: 10.1117/12.908227
Show Author Affiliations
Hans G. Breunig, JenLab GmbH (Germany)
Martin Weinigel, JenLab GmbH (Germany)
Karsten König, JenLab GmbH (Germany)
Saarland Univ. (Germany)

Published in SPIE Proceedings Vol. 8225:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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