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Proceedings Paper

Angular domain spectroscopic imaging for breast cancer margin assessment after lumpectomy
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Paper Abstract

Angular Domain Spectroscopic Imaging (ADSI) is a novel technique for the detection and characterization of optical contrast abnormalities in ex-vivo breast tissue samples based on spectral characteristics. The imaging system employs a spatial filter called an angular filter array to reject scattered photons traversing a sample. The system employs an imaging spectrometer to capture and discriminate the largely remaining quasi-ballistic photons based on spatial position and wavelength. Spectral data were obtained from samples obtained from two patients, one sample contained invasive mammary carcinoma, and the other one contained normal fat and fibrous tissue. Principal component analysis using transmission absorption spectra obtained with ADSI was able to differentiate tumor versus normal tissue regions.

Paper Details

Date Published: 16 February 2012
PDF: 6 pages
Proc. SPIE 8220, Optical Biopsy X, 822003 (16 February 2012); doi: 10.1117/12.907635
Show Author Affiliations
Fartash Vasefi, Lawson Health Research Institute (Canada)
Univ. of Western Ontario (Canada)
Simon Fraser Univ. (Canada)
Mohamadreza Najiminaini, Lawson Health Research Institute (Canada)
Simon Fraser Univ. (Canada)
Astrid Chamson-Reig, Lawson Health Research Institute (Canada)
Muriel Brackstone, London Regional Cancer Program (Canada)
Univ. of Western Ontario (Canada)
Bozena Kaminska, Simon Fraser Univ. (Canada)
Jeffrey J. L. Carson, Lawson Health Research Institute (Canada)
Univ. of Western Ontario (Canada)

Published in SPIE Proceedings Vol. 8220:
Optical Biopsy X
Robert R. Alfano; Stavros G. Demos, Editor(s)

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