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Proceedings Paper

Variation analysis of flow rate delivered using a blister pump
Author(s): Sivesh Selvakumar; Rodrigo Linares; Aaron Oppenheimer; Brian Anthony
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Paper Abstract

Components for on-chip storage and delivery of liquid reagent are necessary for many commercial applications of lab-on- a-chip technology. One such system uses a 'blister-pack' that is pushed by an actuator. This paper explores the sensitivity of the flow rate produced by a blister-actuator pair to the expected manufacturing variations in its dimensions. A numerical model of the blister-actuator pair is developed and the tool of Variation Simulation Modeling (VSM) is used to determine the robustness of fluid delivery. For a flow-rate requirement of +/- 10%, the number of out-of-spec parts is found to be less than 0.01%. The critical dimensions that need to be controlled to improve robustness are also identified.

Paper Details

Date Published: 14 February 2012
PDF: 6 pages
Proc. SPIE 8251, Microfluidics, BioMEMS, and Medical Microsystems X, 82510I (14 February 2012); doi: 10.1117/12.907502
Show Author Affiliations
Sivesh Selvakumar, St. Jude Medical, Inc. (United States)
Rodrigo Linares, Natel Energy, Inc. (United States)
Aaron Oppenheimer, Daktari Diagnostics, Inc. (United States)
Brian Anthony, Massachusetts Institute of Technology (United States)

Published in SPIE Proceedings Vol. 8251:
Microfluidics, BioMEMS, and Medical Microsystems X
Holger Becker; Bonnie L. Gray, Editor(s)

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