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Proceedings Paper

4D imaging of embryonic chick hearts by streak-mode Fourier domain optical coherence tomography
Author(s): Rui Wang; Julie X. Yun; Richard Goodwin; Roger Markwald; Thomas K. Borg; Raymond B. Runyan; Bruce Gao
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Paper Abstract

Recently, we developed the streak-mode Fourier domain optical coherence tomography (OCT) technique in which an area-scan camera is used in a streak-mode to record the OCT spectrum. Here we report the application of this technique to in ovo imaging HH18 embryonic chick hearts with an ultrahigh speed of 1,016,000 axial scans per second. The high-scan rate enables the acquisition of high temporal resolution 2D datasets (1,000 frames per second or 1 ms between frames) and 3D datasets (10 volumes per second), without use of prospective or retrospective gating technique. This marks the first time that the embryonic animal heart has been 4D imaged using a megahertz OCT.

Paper Details

Date Published: 17 February 2012
PDF: 6 pages
Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 82073V (17 February 2012); doi: 10.1117/12.907156
Show Author Affiliations
Rui Wang, Clemson Univ. (United States)
Julie X. Yun, Clemson Univ. (United States)
Richard Goodwin, Univ. of South Carolina (United States)
Roger Markwald, Medical Univ. of South Carolina (United States)
Thomas K. Borg, Medical Univ. of South Carolina (United States)
Raymond B. Runyan, The Univ. of Arizona (United States)
Bruce Gao, Clemson Univ. (United States)

Published in SPIE Proceedings Vol. 8207:
Photonic Therapeutics and Diagnostics VIII
Anita Mahadevan-Jansen; Andreas Mandelis; Kenton W. Gregory; Nikiforos Kollias; Hyun Wook Kang; Henry Hirschberg; Melissa J. Suter; Brian Jet-Fei Wong; Justus F. Ilgner; Stephen Lam; Bodo E. Knudsen; Steen Madsen; E. Duco Jansen; Bernard Choi; Guillermo J. Tearney; Laura Marcu; Haishan Zeng; Matthew Brenner; Krzysztof Izdebski, Editor(s)

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