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Proceedings Paper

Visualization of human retinal capillary networks: a comparison of intensity, speckle-variance and phase-variance optical coherence tomography
Author(s): Dae Yu Kim; Jeff Fingler; John S. Werner; Daniel M. Schwartz; Scott E. Fraser; Robert J. Zawadzki
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Paper Abstract

We evaluate methods to visualize human retinal micro-circulation in vivo by standard intensity-based optical coherence tomography (OCT), speckle-variance optical coherence tomography (svOCT), and phase-variance optical coherence tomography (pvOCT). En face projection views created from the same volumetric data set of the human retina using all three data processing methods are created and compared. Additionally we used support vector machine (SVM) based semi-automatic segmentation to generate en face projection views of individual retinal layers. The layers include: first, the whole inner retina (from the nerve fiber layer to the outer nuclear layer), and second, from the ganglion cell layer to the outer nuclear layer. Finally, we compare the retinal vasculature images processed from the three OCT techniques and fluorescein angiography (FA).

Paper Details

Date Published: 1 February 2012
PDF: 6 pages
Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 821307 (1 February 2012); doi: 10.1117/12.906940
Show Author Affiliations
Dae Yu Kim, Univ. of California, Davis (United States)
Jeff Fingler, California Institute of Technology (United States)
John S. Werner, Univ. of California, Davis (United States)
Daniel M. Schwartz, Univ. of California, San Francisco (United States)
Scott E. Fraser, California Institute of Technology (United States)
Robert J. Zawadzki, Univ. of California, Davis (United States)


Published in SPIE Proceedings Vol. 8213:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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