Share Email Print
cover

Proceedings Paper

Analysis of spectral-phase conventional and long-range surface plasmon resonance biosensors
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We have analyzed and compared the spectral differential phase sensing performance for conventional and long-range (LR) surface plasmon resonance (SPR) across a wide sample refractive index range (i.e. dynamic range) of 1.3330- 1.3505 using Fresnel's Equations and Transfer Matrix method. We demonstrate that wide-range detection limit as high as 7.9×10-9 RIU (Refractive Index Unit) for conventional SPR can be achieved with a set of optimized sensing parameters and a phase measurement resolution of 2×10-4 rad, whereas best detection limit for LRSPR is lower. We have also investigated for the effect of sensing parameters including angle of incidence, metal film material and thickness. LRSPR is found to be quite tolerant to the choice of material and thickness of metal film. This work presents a comprehensive comparison between conventional and LR SPR for spectral-phase configuration.

Paper Details

Date Published: 6 February 2012
PDF: 9 pages
Proc. SPIE 8234, Plasmonics in Biology and Medicine IX, 823414 (6 February 2012); doi: 10.1117/12.906756
Show Author Affiliations
Cheng Wang, The Chinese Univ. of Hong Kong (Hong Kong, China)
Tsinghua Univ. (China)
Ho-Pui Ho, The Chinese Univ. of Hong Kong (Hong Kong, China)
Ping Shum, Nanyang Technological Univ. (Singapore)


Published in SPIE Proceedings Vol. 8234:
Plasmonics in Biology and Medicine IX
Tuan Vo-Dinh; Joseph R. Lakowicz, Editor(s)

© SPIE. Terms of Use
Back to Top