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Proceedings Paper

High frequency intravascular photoacoustic (IVPA) imaging for differentiating arterial wall layered structures
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Paper Abstract

Arterial wall is composed of three layers: intima, media and adventitia. Intima-media thickness (IMT) is an important prognostic indicator of atherosclerotic diseases. Although intravascular ultrasound (IVUS) imaging is a commonly used method for delineation of the layered structures, it is inferior to the optical absorption contrast offered by intravascular photoacoustic (IVPA) imaging. We introduce an integrated miniature probe that combines the capabilities of IVUS and IVPA imaging for the evaluation of arterial wall layered structures. Healthy rabbit aorta was imaged ex vivo. IVPA results showed superior contrast over IVUS in identifying the layered structures of arterial wall.

Paper Details

Date Published: 9 February 2012
PDF: 4 pages
Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 820746 (9 February 2012); doi: 10.1117/12.906581
Show Author Affiliations
Xiang Li, The Univ. of Southern California (United States)
Wei Wei, Beckman Laser Institute and Medical Clinic (United States)
Wuhan Univ. (China)
Qifa Zhou, The Univ. of Southern California (United States)
K. Kirk Shung, The Univ. of Southern California (United States)
Zhongping Chen, Beckman Laser Institute and Medical Clinic (United States)
Edwards Lifesciences Ctr. for Advanced Cardiovascular Technology (United States)
Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 8207:
Photonic Therapeutics and Diagnostics VIII
Anita Mahadevan-Jansen; Andreas Mandelis; Kenton W. Gregory; Nikiforos Kollias; Hyun Wook Kang; Henry Hirschberg; Melissa J. Suter; Brian Jet-Fei Wong; Justus F. Ilgner; Stephen Lam; Bodo E. Knudsen; Steen Madsen; E. Duco Jansen; Bernard Choi; Guillermo J. Tearney; Laura Marcu; Haishan Zeng; Matthew Brenner; Krzysztof Izdebski, Editor(s)

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