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Proceedings Paper

Non-invasive blood flow measurements using ultrasound modulated diffused light
Author(s): N. Racheli; A. Ron; Y. Metzger; I. Breskin; G. Enden; M. Balberg; R. Shechter
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Paper Abstract

Adequate capillary blood flow is a critical parameter for tissue vitality. We present a novel non-invasive method for measuring blood flow based on the acousto-optic effect, using ultrasound modulated diffused light. The benefits of the presented method are: deep tissue sampling (> 1cm), continuous real time measurement, simplicity of apparatus and ease of operation. We demonstrate the ability of the method to measure flow of scattering fluid using a calibrated flow phantom model. Fluid flow was generated by a calibrated syringe pump and the phantom's sampled volume contained millimeter size flow channels. Results demonstrate linear dependence of flow as measured by the presented technique (CFI) to actual flow values with R2=0.91 in the range of 0 to 2 ml/min, and a linear correlation to simultaneous readings of a laser Doppler probe from the same phantom. This data demonstrates that CFI readings provide a non-invasive platform form measuring tissue microcirculatory blood flow.

Paper Details

Date Published: 23 February 2012
PDF: 8 pages
Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 82232A (23 February 2012); doi: 10.1117/12.906342
Show Author Affiliations
N. Racheli, Ornim Medical Ltd. (Israel)
A. Ron, Ornim Medical Ltd. (Israel)
Y. Metzger, Ornim Medical Ltd. (Israel)
I. Breskin, Ornim Medical Ltd. (Israel)
G. Enden, Ben-Gurion Univ. of the Negev (Israel)
M. Balberg, Ornim Medical Ltd. (Israel)
R. Shechter, Ornim Medical Ltd. (Israel)


Published in SPIE Proceedings Vol. 8223:
Photons Plus Ultrasound: Imaging and Sensing 2012
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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