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Proceedings Paper

Optical coherence tomography vs. high-frequency ultrasound during noninvasive laser coagulation of the canine vas deferens
Author(s): Christopher M. Cilip; Mohamad E. Allaf; Nathaniel M. Fried
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Paper Abstract

A noninvasive approach to vasectomy may eliminate male fear of complications related to surgery and increase its acceptance. Noninvasive laser thermal occlusion of the canine vas deferens has recently been reported. In this study, optical coherence tomography (OCT) and high-frequency ultrasound (HFUS) are compared for monitoring laser thermal coagulation of the vas in an acute canine model. Bilateral noninvasive laser coagulation of the vas was performed in 6 dogs (n=12 vasa) using a Ytterbium fiber laser wavelength of 1075 nm, incident power of 9.0 W, pulse duration of 500 ms, pulse rate of 1 Hz, and 3-mm-diameter spot. Cryogen spray cooling was used to prevent skin burns during the procedure. An OCT system with endoscopic probe and a HFUS system with 20-MHz transducer were used to image the vas immediately before and after the procedure. Vasa were then excised and processed for gross and histologic analysis for comparison with OCT and HFUS images. OCT provided high-resolution, superficial imaging of the compressed vas within the vas ring clamp, while HFUS provided deeper imaging of the vas held manually in the scrotal fold. Both OCT and high HFUS are promising imaging modalities for real-time confirmation of vas occlusion during noninvasive laser vasectomy.

Paper Details

Date Published: 9 February 2012
PDF: 7 pages
Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 820715 (9 February 2012); doi: 10.1117/12.905259
Show Author Affiliations
Christopher M. Cilip, The Univ. of North Carolina at Charlotte (United States)
Mohamad E. Allaf, The Johns Hopkins Univ. (United States)
Nathaniel M. Fried, The Univ. of North Carolina at Charlotte (United States)
The Johns Hopkins Univ. (United States)


Published in SPIE Proceedings Vol. 8207:
Photonic Therapeutics and Diagnostics VIII
Anita Mahadevan-Jansen; E. Duco Jansen; Andreas Mandelis; Kenton W. Gregory; Guillermo J. Tearney; Laura Marcu; Nikiforos Kollias; Bernard Choi; Haishan Zeng; Melissa J. Suter; Stephen Lam; Matthew Brenner; Hyun Wook Kang; Bodo E. Knudsen; Henry Hirschberg; Steen Madsen; Brian Jet-Fei Wong; Justus F. Ilgner; Krzysztof Izdebski, Editor(s)

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