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Proceedings Paper • Open Access

Biomedical spectral x-ray imaging: promises and challenges
Author(s): Steven M. Jorgensen; Diane R. Eaker; Erik L. Ritman

Paper Abstract

Imaging arrays with sub-millimeter detector pixels that count and allocate energy to each detected photon are now being introduced into biomedical computed tomography scanners. Consequently, bremsstrahlung x-ray can provide the advantages of simultaneous recording of multiple quasi-monochromatic x-ray images which can be used for identification of various materials within the image field. This capability increases the inherent contrast within biomedical CT images and also introduces the ability to use high atomic weight "foreign" elements (e.g., strontium) which are surrogates for "native" biological elements (e.g., calcium) to monitor tissue function (e.g., bone deposition). Challenges for this methodology include limited maximum fluence due to photon pile-up, charge-sharing between contiguous pixels and heterogeneous pixel characteristics due to manufacturing difficulties.

Paper Details

Date Published: 15 September 2011
PDF: 10 pages
Proc. SPIE 8143, Medical Applications of Radiation Detectors, 814302 (15 September 2011); doi: 10.1117/12.904615
Show Author Affiliations
Steven M. Jorgensen, Mayo Clinic College of Medicine (United States)
Diane R. Eaker, Mayo Clinic College of Medicine (United States)
Erik L. Ritman, Mayo Clinic College of Medicine (United States)

Published in SPIE Proceedings Vol. 8143:
Medical Applications of Radiation Detectors
H. Bradford Barber; Hans Roehrig; Douglas J. Wagenaar, Editor(s)

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