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Proceedings Paper

Screening prostate cancer using a portable near infrared scanning imaging unit with an optical fiber-based rectal probe
Author(s): Yang Pu; Wubao Wang; Guichen Tang; Yury Budansky; Mikhail Sharonov; Min Xu; Samuel Achilefu; James A. Eastham; Robert R. Alfano
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Paper Abstract

A portable near infrared scanning polarization imaging unit with an optical fiber-based rectal probe, namely Photonic Finger, was designed and developed o locate the 3D position of abnormal prostate site inside normal prostate tissue. An inverse algorithm, Optical Tomography using Independent Component Analysis (OPTICA) was improved particularly to unmix the signal from targets (cancerous tissue) embedded in a turbid medium (normal tissue) in the backscattering imaging geometry. Photonic Finger combined with OPTICA was tested to characterize different target(s) inside different tissue medium, including cancerous prostate tissue embedded by large piece of normal tissue.

Paper Details

Date Published: 1 February 2012
PDF: 8 pages
Proc. SPIE 8220, Optical Biopsy X, 822002 (1 February 2012); doi: 10.1117/12.904254
Show Author Affiliations
Yang Pu, The City College of New York (United States)
Wubao Wang, The City College of New York (United States)
Guichen Tang, The City College of New York (United States)
Yury Budansky, The City College of New York (United States)
Mikhail Sharonov, The City College of New York (United States)
Min Xu, Fairfield Univ. (United States)
Samuel Achilefu, Washington Univ. School of Medicine in St. Louis (United States)
James A. Eastham, Memorial Sloan-Kettering Cancer Ctr. (United States)
Robert R. Alfano, The City College of New York (United States)


Published in SPIE Proceedings Vol. 8220:
Optical Biopsy X
Robert R. Alfano; Stavros G. Demos, Editor(s)

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