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Proceedings Paper

Optoelectronic tweezers for medical diagnostics
Author(s): Clemens Kremer; Steven Neale; Anoop Menachery; Mike Barrett; Jonathan M. Cooper
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Paper Abstract

Optoelectronic tweezers (OET) allows the spatial patterning of electric fields through selected illumination of a photoconductive surface. This enables the manipulation of micro particles and cells by creating non-uniform electrical fields that then produce dielectrophoretic (DEP) forces. The DEP responses of cells differ and can produce negative or positive (repelled or attracted to areas of high electric field) forces. Therefore OET can be used to manipulate individual cells and separate different cell types from each other. Thus OET has many applications for medical diagnostics, demonstrated here with work towards diagnosing Human African Trypanosomiasis, also known as sleeping sickness.

Paper Details

Date Published: 1 February 2012
PDF: 7 pages
Proc. SPIE 8212, Frontiers in Biological Detection: From Nanosensors to Systems IV, 82120E (1 February 2012); doi: 10.1117/12.903944
Show Author Affiliations
Clemens Kremer, Univ. of Glasgow (United Kingdom)
Steven Neale, Univ. of Glasgow (United Kingdom)
Anoop Menachery, Univ. of Glasgow (United Kingdom)
Mike Barrett, Univ. of Glasgow (United Kingdom)
Jonathan M. Cooper, Univ. of Glasgow (United Kingdom)


Published in SPIE Proceedings Vol. 8212:
Frontiers in Biological Detection: From Nanosensors to Systems IV
Benjamin L. Miller; Philippe M. Fauchet, Editor(s)

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