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Proceedings Paper

Whole field reflectance optical tomography
Author(s): Nicolás A. Carbone; Héctor A. García; Héctor O. Di Rocco; Daniela I. Iriarte; Juan A. Pomarico; Héctor F. Ranea Sandoval
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Paper Abstract

Optical imaging through highly scattering media such as biological tissues is a topic of intense research, especially for biomedical applications. Diverse optical systems are currently under study and development for displaying the functional imaging of the brain and for the detection of breast tumors. From the theoretical point of view, a suitable description of light propagation in tissues involves the Radiative Transfer Equation, which considers the energetic aspects of light propagation. However, this equation cannot be solved analytically in a closed form and the Diffusion Approximation is normally used. Experimentally it is possible to use Transmission or Reflection geometries and Time Resolved, Frequency Modulated or CW sources. Each configuration has specific advantages and drawbacks, depending on the desired application. In the present contribution, we investigate the reflected light images registered by a CCD camera when scattering and absorbing inhomogeneities are located at different depths inside turbid media. This configuration is of particular interest for the detection and optical characterization of changes in blood flow in organs, as well as for the detection and characterization of inclusions in those cases for which the transmission slab geometry is not well suited. Images are properly normalized to the background intensity and allow analyzing relative large areas (typically 5 × 5 cm2) of the tissue. We tested the proposal using Numerical Monte Carlo simulations implemented in a Graphic Processing Unit (Video accelerating Card). Calculations are thus several orders of magnitude faster than those run in CPU. Experimental results in phantoms are also given.

Paper Details

Date Published: 2 November 2011
PDF: 7 pages
Proc. SPIE 8011, 22nd Congress of the International Commission for Optics: Light for the Development of the World, 80118J (2 November 2011); doi: 10.1117/12.901946
Show Author Affiliations
Nicolás A. Carbone, Univ. Nacional del Ctr. de la Provincia de Buenos Aires (Argentina)
Héctor A. García, Univ. Nacional del Ctr. de la Provincia de Buenos Aires (Argentina)
Héctor O. Di Rocco, Univ. Nacional del Ctr. de la Provincia de Buenos Aires (Argentina)
Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina)
Daniela I. Iriarte, Univ. Nacional del Ctr. de la Provincia de Buenos Aires (Argentina)
Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina)
Juan A. Pomarico, Univ. Nacional del Ctr. de la Provincia de Buenos Aires (Argentina)
Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina)
Héctor F. Ranea Sandoval, Univ. Nacional del Ctr. de la Provincia de Buenos Aires (Argentina)
Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina)


Published in SPIE Proceedings Vol. 8011:
22nd Congress of the International Commission for Optics: Light for the Development of the World
Ramón Rodríguez-Vera; Ramón Rodríguez-Vera; Ramón Rodríguez-Vera; Rufino Díaz-Uribe; Rufino Díaz-Uribe; Rufino Díaz-Uribe, Editor(s)

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