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Proceedings Paper

Depth selectivity in biological tissues by polarization analysis of backscattered light
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Paper Abstract

Depth selectivity is crucial for accurate depth volume probing in vivo in a large number of medical applications such as brain monitoring. Polarization gating has been widely used to analyze biological tissues. It is shown that using polarized light allows probing tissues on a specific depth depending on the polarization illumination type (linearly, circularly) and the tissues properties. However, accurate depth investigation of the tissue requires a high selectivity of the probed depth. We propose and simulate the use of different elliptically polarized illuminations for continuous depth examination between linearly and circularly polarized illumination. Monte Carlo simulations verify that circularly polarized illumination penetrates deeper than linearly polarized illumination in biological scattering media. Furthermore, we show that elliptically polarized light can be tuned in its penetration depth continuously between the penetration depth of linearly polarized light and circularly polarized light. Experimental results obtained on phantoms mimicking in vivo situations are presented.

Paper Details

Date Published: 30 September 2011
PDF: 7 pages
Proc. SPIE 8172, Optical Complex Systems: OCS11, 817205 (30 September 2011); doi: 10.1117/12.898618
Show Author Affiliations
Anabela da Silva, Institut Fresnel, CNRS, Aix-Marseille Univ. (France)
Pierre Stahl, Institut de Neurosciences Cognitives, CNRS, Aix-Marseille Univ. (France)
Simon Rehn, Institut Fresnel, CNRS, Aix-Marseille Univ. (France)
I. Vanzetta, Institut de Neurosciences Cognitives, CNRS, Aix-Marseille Univ. (France)
Carole Deumié, Institut Fresnel, CNRS, Aix-Marseille Univ. (France)


Published in SPIE Proceedings Vol. 8172:
Optical Complex Systems: OCS11
Gérard Berginc, Editor(s)

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