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Proceedings Paper

A novel SPECT camera for molecular imaging of the prostate
Author(s): Alan Cebula; David Gilland; Li-Ming Su; Douglas Wagenaar; Amir Bahadori
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Paper Abstract

The objective of this work is to develop an improved SPECT camera for dedicated prostate imaging. Complementing the recent advancements in agents for molecular prostate imaging, this device has the potential to assist in distinguishing benign from aggressive cancers, to improve site-specific localization of cancer, to improve accuracy of needle-guided prostate biopsy of cancer sites, and to aid in focal therapy procedures such as cryotherapy and radiation. Theoretical calculations show that the spatial resolution/detection sensitivity of the proposed SPECT camera can rival or exceed 3D PET and further signal-to-noise advantage is attained with the better energy resolution of the CZT modules. Based on photon transport simulation studies, the system has a reconstructed spatial resolution of 4.8 mm with a sensitivity of 0.0001. Reconstruction of a simulated prostate distribution demonstrates the focal imaging capability of the system.

Paper Details

Date Published: 15 September 2011
PDF: 10 pages
Proc. SPIE 8143, Medical Applications of Radiation Detectors, 814305 (15 September 2011); doi: 10.1117/12.896235
Show Author Affiliations
Alan Cebula, Univ. of Florida (United States)
David Gilland, Univ. of Florida (United States)
Li-Ming Su, Univ. of Florida (United States)
Douglas Wagenaar, Children's Hospital of Los Angeles (United States)
Amir Bahadori, Univ. of Florida (United States)

Published in SPIE Proceedings Vol. 8143:
Medical Applications of Radiation Detectors
H. Bradford Barber; Hans Roehrig; Douglas J. Wagenaar, Editor(s)

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