Share Email Print

Proceedings Paper

Resolution limits between objects embedded in breast-like slab using the optical frequency-domain method: a numerical approach
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Optical methods allow investigating biological tissue noninvasively without ionizing radiations. Moreover, considering low absorption processes in the tissue in the near-infrared wavelengths range, biological tissue can be deeply investigated. In this field, we studied the resolution limits of the detection of one and two tumour-like heterogeneities embedded in the middle plane of a slab that mimics a breast enclosed between two transparent plates. We used the diffusion equation in order to model the photons propagation in such slab. It is solved in the time-domain by means of a finite element method. We computed time-resolved trans-illumination data based on lateral scan of the slab. The timedependent transmitted light, received at the opposite of the source, was transformed in the frequency-domain and the modulation and phase-shift of the signal are then obtained. The resulting phase-shift considering the embedded objects was analyzed versus the distance between the objects. Then, the resolution limits were estimated considering different modulation frequencies and a noise level. The overall combinations took into account a set of optical properties that mimics realistic optical properties for healthy breast tissue and tumours.

Paper Details

Date Published: 8 June 2011
PDF: 8 pages
Proc. SPIE 8092, Medical Laser Applications and Laser-Tissue Interactions V, 80920O (8 June 2011); doi: 10.1117/12.890002
Show Author Affiliations
Vianney Piron, ENSAM CER d'Angers (France)
Jean-Pierre L'Huillier, ENSAM CER d'Angers (France)

Published in SPIE Proceedings Vol. 8092:
Medical Laser Applications and Laser-Tissue Interactions V
Ronald Sroka; Lothar D. Lilge, Editor(s)

© SPIE. Terms of Use
Back to Top