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Proceedings Paper

Mechanical compression for contrasting OCT images of biotissues
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Paper Abstract

Contrasting of biotissue layers in OCT images after application of mechanical compression is discussed. The study is performed on ex vivo samples of human rectum, and in vivo on skin of human volunteers. We show that mechanical compression provides contrasting of biotissue layer boundaries due to different mechanical properties of layers. We show that alteration of pressure from 0 up to 0.45 N/mm2 causes contrast increase from 1 to 10 dB in OCT imaging of human rectum ex vivo. Results of ex vivo studies are in good agreement with Monte Carlo simulations. Application of pressure of 0.45 N/mm2 causes increase in contrast of epidermis-dermis junction in OCT-images of human skin in vivo for about 10 dB.

Paper Details

Date Published: 1 June 2011
PDF: 7 pages
Proc. SPIE 8091, Optical Coherence Tomography and Coherence Techniques V, 80910N (1 June 2011); doi: 10.1117/12.889844
Show Author Affiliations
Mikhail Yu Kirillin, Institute of Applied Physics (Russian Federation)
Pavel D. Argba, Institute of Applied Physics (Russian Federation)
N. I. Lobachevsky State Univ. of Nizhny Novgorod (Russian Federation)
Vladislav A. Kamensky, Institute of Applied Physics (Russian Federation)


Published in SPIE Proceedings Vol. 8091:
Optical Coherence Tomography and Coherence Techniques V
Rainer A. Leitgeb; Brett E. Bouma, Editor(s)

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