Share Email Print
cover

Proceedings Paper

A porous silicon based microfluidic array for the optical monitoring of biomolecular interactions
Author(s): Emanuele Orabona; Ilaria Rea; Ivo Rendina; Luca De Stefano
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

A porous silicon (PSi) based microarray has been integrated with a microfluidic system based on polydimethylsiloxane (PDMS) channels circuit, as a proof of concept device for the optical monitoring of selective label-free DNA-DNA interaction. Theoretical calculations, based on finite element method, taking into account molecular interactions, are in good agreement with the experimental results, and the developed numerical model can be used for device optimization. The functionalization process and the interaction between probe and target DNA has been monitored by spectroscopic reflectometry for each PSi element in the microchannels.

Paper Details

Date Published: 6 May 2011
PDF: 6 pages
Proc. SPIE 8073, Optical Sensors 2011; and Photonic Crystal Fibers V, 807314 (6 May 2011); doi: 10.1117/12.887256
Show Author Affiliations
Emanuele Orabona, Istituto per la Microelettronica e Microsistemi, CNR (Italy)
Ilaria Rea, Istituto per la Microelettronica e Microsistemi, CNR (Italy)
Ivo Rendina, Istituto per la Microelettronica e Microsistemi, CNR (Italy)
Luca De Stefano, Istituto per la Microelettronica e Microsistemi, CNR (Italy)


Published in SPIE Proceedings Vol. 8073:
Optical Sensors 2011; and Photonic Crystal Fibers V
Kyriacos Kalli; Francesco Baldini; Jiri Homola; Robert A. Lieberman, Editor(s)

© SPIE. Terms of Use
Back to Top